# Butterfly Effect — Institutional Target Shortlist Date: 2026-03-26 ## Purpose This shortlist is not a generic outreach list. It is a prioritized set of groups and organizations whose public research posture suggests a realistic fit for the current Butterfly Effect bottlenecks. Current bottleneck: - cross-cohort nightly transport for stress Secondary need: - institutionally generated longitudinal datasets with participant-night linkage, repeated burden outcomes, cardiovascular or movement signal, and basic confounders ## Priority lanes ### Lane A — Physiology-rich sleep and circadian programs These are the highest-value targets when the goal is participant-night data with stronger clinical or physiological grounding. #### 1. Brigham and Women's Hospital — Division of Sleep and Circadian Disorders - Priority: `P1` - Why now: large sleep and circadian program with clinical care, sleep testing, and explicit research function. - Exact ask: longitudinal participant-night sleep data with repeated stress or symptom burden, plus physiology-rich subset if available. - Best fit: hospital pilot, sleep disorders cohort, physiology-rich nightly route validation. - Source: #### 2. Stanford Medicine — Center for Sleep and Circadian Sciences - Priority: `P1` - Why now: interdisciplinary sleep and circadian research spanning technology, clinical trials, and translational work. - Exact ask: actigraphy or wearable-linked nightly datasets with repeated next-day burden or behavioral outcomes. - Best fit: wearable-linked academic cohort, timing and physiology transport work. - Source: #### 3. Northwestern University / Northwestern Medicine — CSCB + Center for Circadian & Sleep Medicine - Priority: `P1` - Why now: unified program across basic, clinical, and translational sleep research with an affiliated sleep health center and explicit collaboration routes. - Exact ask: participant-night sleep datasets with repeated burden outcomes, especially where clinical sleep phenotyping and wearable physiology can be linked. - Best fit: mixed clinical/research cohort with strong circadian or sleep phenotyping. - Sources: - - #### 4. Hospital Clínic Barcelona — Unit of Sleep Research - Priority: `P1` - Why now: multidisciplinary sleep research across psychiatry, psychology, pulmonology, neurology, biomarkers, and new diagnostic tools including apps and AI. - Exact ask: longitudinal sleep disorder cohorts with participant-night rows, repeated burden outcomes, and biomarker or PSG subset if available. - Best fit: European hospital collaboration, physiology-rich sleep disorder cohort. - Source: ### Lane B — Digital trials and wearable-first cohorts These are strong targets when the goal is repeated outcomes plus longitudinal wearable data outside a classical sleep lab. #### 5. Scripps Research — Digital Trials Center - Priority: `P1` - Why now: site-less research model built around digital technologies, with explicit work in sleep medicine and direct contact path. - Exact ask: participant-night exports from digital cohorts with sleep, HR, activity, and repeated daily or weekly burden endpoints. - Best fit: wearable-native cohort, remote longitudinal pilot, rapid feasibility assessment. - Contact route: `dtc@scripps.edu` - Sources: - - #### 6. Duke University Population Research Institute — RAISE / mobile stress study line - Priority: `P1` - Why now: explicit field-based work on daily stress, EMA, connectedness, and commercial wearables capturing heart rate, skin temperature, movement, and sleep quality. - Exact ask: repeated stress-linked wearable cohorts, especially those preserving participant-day or participant-night linkage. - Best fit: daily stress / wearable physiology bridge, daily-to-night interpretation support. - Contact route: `contactdupri@duke.edu` - Source: ### Lane C — Platform and device partners for prospective pilots These are not the first choice for legacy cohort access. They are the first choice if retrospective data access stalls and the project needs a prospective, instrumentation-controlled pilot. #### 7. Oura for Research - Priority: `P2` - Why now: active research collaboration program, sleep and HRV coverage, academic medical center footprint, and explicit research solution. - Exact ask: prospective pilot or access path through an existing academic collaborator using Oura data with repeated stress or symptom reporting. - Best fit: prospective wearable cohort, high adherence, nightly physiology and sleep timing. - Source: #### 8. Empatica — Health Monitoring Platform / Research Portal - Priority: `P2` - Why now: research portal supports longitudinal and clinical studies with raw and summary data, academic research use case, and direct team contact. - Exact ask: prospective study with autonomic, movement, and sleep-relevant physiology, especially where raw data access matters. - Best fit: physiology-heavy remote monitoring pilot, digital biomarker development, actigraphy-rich substudies. - Sources: - - #### 9. Withings Health Solutions - Priority: `P2` - Why now: explicit clinical trial and research pathway, sleep analyzer product line, direct study request path. - Exact ask: prospective institutional pilot combining nightly sleep summaries with repeated burden outcomes and optional home sleep hardware. - Best fit: home sleep deployment, hospital-partnered remote monitoring pilot. - Source: ## How to use this shortlist Use it in order: 1. Lane A first if the goal is transport-ready participant-night datasets. 2. Lane B next if the goal is repeated stress and wearable coverage. 3. Lane C if the project needs a prospective pilot rather than retrospective cohort access. ## Recommended first outreach bundle For the first message or first call, send: - institutional one-pager - institutional variable shortlist - data requirements pack - target-specific ask from the outreach templates ## Current recommendation Do not open with broad partnership language. Open with one narrow ask: - one cohort - one endpoint family - one feasibility review - one realistic data handoff path